Evolution of HLA Genes

How does selection shape genetic differentiation? Comparing differentiation at selected and neutral loci, we uncover the dynamics of selection.

Human Population Genetics

Which genes are under balancing selection? We have developed a test to identify targets of selection, and explore their biological importance.

Admixed Populations

Can we detect recent selection in the genome of admixed populations? Recent selection can cause changes in ancestry proportions. Is this visible in admixed Brazilians?

Immunological Transcriptomics

Expression estimate and eQTL mapping in HLA Genes